Young stroke causes

Consider a different aetiology in patients <40 year old

SCAM DISC

  • Syphilis
  • Carotid/vertebral artery dissection
  • Antiphospholipid syndrome
  • Mitochondrial disease, see below
  • Drug induced e.g. cocaine
  • Inherited thrombophilia (usually venous sinus thrombosis)
  • Structural abnormalities of extracranial vessels e.g. moya moya disease
  • Cerebral vasculitis e.g. SLE

Mitochondrial disease e.g. MELAS

  • Mitochondrial Encephalopathy
  • Lactic Acidosis
  • Stroke-like episodes
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