Sodium valproate side-effects

VALPROATE

  • Valproate
  • Appetite increase, so weight gain
  • Liver failure (monitor LFTs during 1st 6 months)
  • Pancreatitis
  • Reversible hair loss (grows back curly, apparently)
  • Oedema
  • Ataxia
  • Teratogenicity, Tremor, Thrombocytopaenia
  • Encephalopathy (due to hyperammonaemia) / Enzyme inducer
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